Noocube is a kind of upgraded version of Alpha Brain. It contains many of the same ingredients; the difference is, Noocube actually reveals the ingredient serving sizes instead of hiding behind proprietary blends. In terms of effectiveness, we think Noocube will improve short-term memory function and reduce performance-anxiety. Most users will see an increase in learning capacity after about 8 weeks. But apart from that, Noocube offers very little. There’s no real ‘kick’ to this nootropic. It’s weak compared to the competition.
Noocube Review: What does this nootropic do?
Noocube is one of the most talked-about nootropics online. It has been on the market for years now, and it has remained popular since its launch. A lot of nootropics and bio-hacking sites give Noocube 5-star reviews; some even say it is the best nootropic currently on the market.
Is Noocube really that good?
What does it do and who is it designed for?
According to the Noocube website, this nootropic is a “synergistic blend of nootropics which helps support and enhance your focus, mental speed and memory”. The site goes on to say that Noocube provides all of the “essential building blocks for a healthy, well-functioning brain”.
More specifically, Noocube claims to deliver the following benefits:
- Enhance focus and concentration
- Improve memory
- Enhance learning capacity
- Improve multitasking
- Increase mental energy
It sounds like Noocube is meant to be a complete, full-spectrum, daily nootropic. It claims to cover every aspect of cognitive function, from memory to multitasking.
One thing that isn’t mentioned on the Noocube website is stress. For us, reducing stress is an important part of a complete nootropic. The best brain supplements all provide something to combat anxiety.
It will be interesting to see if Noocube does give us this vital component or not.
Does Noocube actually do any of these things though? Is it safe? Does Noocube help with learning? Is it the best nootropic around today? In our in-depth Noocube review below, we answer all of these questions and more!
Here is the Noocube formula as displayed on the bottle:
For those of you that can’t quite make that out, here is a full list of the ingredients in Noocube:
- L-Tyrosine, 250 mg
- Cat’s Claw, 175 mg
- Bacopa Monnieri Extract, 250 mg
- Alpha GPC, 50 mg
- L-Theanine, 100 mg
- Huperzia Serrata (0,5 % Huperzine-A), 20 mg
- Oat Straw Extract, 150 mg
- Resveratrol, 14.3 mg
- Pterostilbene, 140 mcg
Here is a quick overview of the ingredients in Noocube. In each case, we’ll tell you what they do, how well we think they work, and what we make of the science behind them. We will also tell you what we make of the dose. As always, post your questions in the comments.
Bacopa monnieri (20% bacosides) – 250mg
Bacopa monnieri is perhaps the best natural memory enhancer in existence. It certainly has some of the most robust scientific proof behind it. Bacopa monnieri has been shown to significantly improve performance in memory-based cognitive tests. It shows particular promise among older people experiencing mild cognitive impairment. It works primarily by encouraging neuron dendrite growth.
Taking 250mg per day will produce real benefits in about 6-12 weeks. The 20% bacoside extract used in Noocube is standard, although top-tier nootropics use a more refined extract than this.
L-Tyrosine – 250mg
Tyrosine is a natural anxiolytic. It reduces anxiety and sharpens focus during times of acute mental and physical stress. Studies show that supplementing with Tyrosine improves cognitive function in people placed in stressful situations. It promotes focus in people who are sleep deprived, exposed to extreme cold, exposed to loud noises, and people who are subjected to intense multitasking. Again, the 250mg we get from Noocube is plenty.
Cat’s Claw Extract (4:1) – 175mg
As far as we’re aware, there is no real evidence that cat’s claw has nootropic properties. We have never seen a convincing study in which humans given cat’s claw saw significant improvements in memory, focus, or any other facet of brain function. Although widely used, we think cart’s claw is a bit of a dud. It has probably been used in Noocube because it was used in Alpha Brain (Noocube’s obvious “inspiration”).
Oat Straw Extract (4:1) – 150mg
Like cat’s claw, we believe that Noocube only contains oat straw because Alpha Brain does. There’s really no other reason why Noocube would use this stuff; it certainly isn’t because oat straw is such a great nootropic! It may have some soothing, mildly anxiolytic properties. But it isn’t a potent nootropic. One study found that it might help elderly people concentrate better, but we’re not completely convinced. More research is needed on this one.
L-Theanine – 100mg
As those of you who read our sleep articles might know already, theanine is a fantastic natural sleep enhancer. It is sometimes used in nootropics because of its synergistic relationship with caffeine. Theanine heightens caffeine’s positive effects and reduces its worst side effects. If you’re drinking a lot of coffee throughout the day – as many nootropics users do – then some added theanine can be a big help. Some say it has focus-enhancing properties of its own, but we’ve not seen any evidence for that.
Alpha-GPC – 50mg
Alpha-GPC is extremely effective for increasing focus, heightening alertness, and improving short-term working memory. It quickly increase choline availability in the brain. This increases the synthesis of acetylcholine – the brain’s executive neurotransmitter – and phosphatidylcholine – a key component of brain cells and a vital part of the cell signalling process. Our only problem here is that Noocube doesn’t contain anywhere near enough Alpha-GPC; just 50mg! The best nootropics contain 200mg or more!
Huperzia Serrate (0.5% Huperzine A) – 20mg
Huperzia Serrata, also known as Chinese clubmoss or toothed clubmoss, is a plant native to India and southeast Asia. It contains very small amounts of a substance called Huperzine A, which is widely used in nootropics today. At 0.5% potency, the Huperzia Serrata in Noocube provides about 100mcg of Huperzine A.
Huperzine A works by inhibiting the enzyme acetylcholinesterase, which destroys acetylcholine after it has passed between neurons. More acetylcholine means more raw brain power. Too much, however, can cause problems, so it must be cycled. As the best ingredients in Noocube take several weeks to have an effect, this might be a mistake!
Resveratrol (99%) – 14.3mg
Resveratrol is a powerful antioxidant found in many fruits and vegetables, although it is most commonly known as the antioxidant prevalent in wine. Resveratrol is a great antioxidant, although it isn’t the most powerful or well absorbed antioxidant to consume orally (which is why red wine isn’t really that good for you). Including 14.3mg of the stuff seems a bit pointless to us. That said, all nootropics need an antioxidant of some kind. Some is better than none!
Pterostilbene – 140mcg
Pterostilbene is an antioxidant closely related to resveratrol. It is often described as a kind of super-charged, more powerful version of resveratrol. There is some merit to these claims; pterostilbene is structurally similar to resveratrol, but it has about 80% bioavailability compared to resveratrol’s 20%. We’re not sure why Noocube uses both antioxidants – we’d have just gone with one and dosed it properly!
Noocube vs Alpha Brain
A lot of people have noticed the similarities between Noocube and Alpha Brain – we’re not alone in this. As such, they want to know which is better; Noocube or Alpha Brain? Here is a quick comparison of the Noocube and Alpha Brain formulas so you can see the similarities:
While Alpha Brain contains a few extra ingredients, and the doses will no doubt be different, you can see that Noocube were clearly “inspired” by Onnit here.
Although Noocube has its flaws, we do always prefer a supplement that is transparent with its ingredients and doses. As such, we’d always opt for Noocube over Alpha Brain.
Our Thoughts On The Noocube Formula
Noocube is not a bad nootropic, all things considered.
Compared to many of the stacks on sale right now, it doesn’t look terrible.
It provides a good dose of Bacopa monnieri, plenty of Tyrosine, and some antioxidants. Together, these ingredients can reduce anxiety, enhance focus, and significantly improve memory function over the long-term.
However, we wont be recommending Noocube to any of our readers. It is a deeply flawed nootropic offering pretty poor value for money.
The formula is not well thought-out; the inclusion of Huperzine A means you have to cycle it, making the Bacopa a lot less effective.
The Alpha-GPC dose is crazy low – other stacks rightly use 4-5 times that much! You aren’t going to see a significant difference in brain function from this much Alpha-GPC; you need to be using 150mg per day at a minimum.
Skimping on such a powerful nootropic, and yet still charging premium prices, isn’t the way to go.
Noocube also contains some useless, unproven ingredients. Oat Straw does nothing; it might act as a weak anxiolytic, but it isn’t as powerful as other substances the manufacturers could have used. Cat’s Claw really lacks any hard scientific proof; in our opinion it’s an overhyped dud.
Compared to the best nootropics on sale right now, Noocube looks weak and uninteresting.
While many people seemingly rave about Noocube, we don’t see what the excitement is all about.
This is a mediocre, boring nootropic. The formula is deeply flawed; these ingredient don’t really work together. Worst of all, it is extremely weak on focus and short-term brain power – just 50mg of Alpha-GPC is ridiculous for this price.
There are better nootropics than Noocube on the market right now. No doubt about that. Noocube is weak and over-priced.
Noocube Side Effects – Is this nootropic safe?
We don’t think you are going to get much out of Noocube in the way of benefits. But you are also unlikely to experience much in the way of side effects from Noocube.
In our opinion, Noocube looks like a safe, side effect-free nootropic supplement.
The Noocube ingredients are all widely used in brain supplements today.
More importantly, they’ve all been tested in robust clinical trials and have been found to be safe for regular, long-term human consumption.
We’ve not seen any evidence that these substances cause serious side effects – the studies rarely report any side effects whatsoever.
However, there is one caveat to that – Huperzine A.
Huperzine A inhibits the enzyme acetylcholinesterase. This causes a steady build-up of acetylcholine in the brain.
More acetylcholine is great, but too much can cause problems. Without an emergency ‘release valve’ to get rid of the excess acetylchloline, levels can quickly become too high. The side effects of having too much acetylcholine in the brain include:
- Loss of focus
- Low mood
We advise taking regular breaks from Huperzine A to allow your acetylchline levels to return to normal. A typical cycle would be 3 weeks on, 10 days off. Ideally, you’d start by taking Noocube for 2 weeks before taking another 2 weeks off and seeing how you go.
So long as you cycle it properly, Noocube appears to be a safe natural nootropic to us.
In Conclusion – Is Noocube a good brain supplement?
Noocube is a weak and over-priced nootropic in our opinion.
The main issue is the fact that the formula has been badly thought out.
You need to regularly cycle Noocube, which means that you are taking regular breaks from Bacopa monnieri. You really need to be taking Bacopa monnieri on a daily basis for 6-8 weeks before the benefits become fully apparent. Taking breaks is not ideal.
Noocube is also laughably weak on focus, concentration and learning. The Alpha-GPC in Noocube should be pulling most of the weight when it comes to information processing and focus enhancement. But Noocube only contains 50mg.
For comparison, other nootropics contain 200mg per serving.
The amount of useless dead weight in the Noocube formula just puts the last nail in the coffin for us.
Noocube is not a terrible nootropic, but it’s far from good. If you want to see a real, meaningful increase in cognitive performance, then you’re going to have to use a more powerful nootropic.
If you want total brain optimization, check out our top rated nootropics.