Natrogix Prime Mind
- Good serving of Ginkgo biloba
- Excellent serving of caffeine
- Cordyceps mushroom doesn't have proven nootropic properties
- Bacoside content of Bacopa monnieri not given - SUSPICIOUS!
- Why DiCaffeine Malate and not just caffeine?
We’re not impressed with Natrogix Prime Mind; not at all. Lots of unproven ingredients really spoil this nootropic. We don’t know why Natrogix Prime Mind uses things like glucuronolactone or cordyceps mushrooms, neither of which have been shown to have brain-boosting properties. Big disappointment.
Natrogix Prime Mind Review: What is it supposed to do?
Natrogix Prime Mind is a brand new nootropic supplement. It has only recently appeared on Amazon. But it has already gained quite a bit of attention. There are several Natrogix Prime Mind reviews online already, and it is getting more customer reviews on Amazon every week. What is Natrogix Prime Mind supposed to do then? Who is it designed for?
According to the manufacturer, Natrogix Prime Mind delivers these key benefits:
- Greater focus and concentration
- Increased energy levels
- Mood support
- Improved mental clarity
The bottle also displays the words “performance +resilience + longevity”.
Clearly then, Prime Mind is supposed to be a complete nootropic. It mentions practically every aspect of cognitive performance. It also mentions general health and wellness goals, such as “resilience” and “longevity”. Natrogix are selling this as a full-spectrum, total optimization stack.
The question we need to answer now is, how much of this is actually true?
Does Natrogix Prime Mind work? Is it safe? Will it cause side effects? Is Prime Mind worth the price? We answer all of these questions in our full Prime Mind review below!
Natrogix Prime Mind Ingredients
Here is the Prime Mind formula as it appears on the bottle:
We will now go through each ingredient and give you a brief overview of its effects, or lack thereof. If you have any questions, please post them in the comments section at the end.
Cordyceps Mushroom – 300mg
This is definitely one of the more fashionable natural nootropics around right now. Cordyceps is being billed as a cure-all on some of the most popular health and fitness blogs. According to some, it is a natural immune system booster. There is definitely evidence to support this claim. Others claim that it is a powerful nootropic – there’s much less evidence to support this claim, however. So far, the only indication that cordyceps mushroom improves learning comes from rodent studies. Even in these results have been unimpressive.
Bacopa monnieri – 300mg
Bacopa monnieri is an adaptogen. It is a central herb in Ayurverdic medicine; it has been used for hundreds of years for a variety of purposes, from curing fever to increasing vitality. We now know that Bacopa monnieri is a powerful memory-enhancer. Supplementation with Bacopa monnieri drastically improves performance in various memory tests in as little as 8 weeks. People with mild, age-related cognitive impairment seem to benefit most, but otherwise healthy, young study participants have also seen big improvements.
Ginkgo biloba – 100mg
Ginkgo biloba is quickly becoming one of the most widely-used natural nootropics in the world. There’s good reason for this – it’s very effective. Ginkgo biloba rapidly increases blood flow in the brain. It causes dilation of your cerebral blood vessels, which allows more blood to reach your brain cells. It also reduces the viscosity of your blood, making it less ‘sticky’ and more fluid. The end result is healthier, better nourished, more effective brain cells.
Glucuronolactone – 100mg
This compound is usually found in energy drinks. It has long been thought to have energy-boosting properties of its own. However, recent studies found this not to be the case. Glucuronolactone does not seem to have any effect on energy, mental clarity, or stamina. Some researchers have urged caution when using this substance because of the lack of long-term studies on its safety. We agree. There is no reason to add this to a nootropic – all risk, no reward.
Dicaffeine Malate – 100mg (73mg of caffeine)
Natrogix probably used Di-Caffeine Malate instead of regular caffeine because this compound is thought to be more “bio-available”. We think this is a big mistake – caffeine already has an effect very quickly after consumption. The malic acid part of this compound does not contribute to better cognitive function – all it has done is displace 27mg of caffeine and given us nothing in return. Purified caffeine anhydrous is always preferable to unusual analogues!
Phosphatidylserine Powder – 25mg
Phosphatidylserine is now used in practically every nootropic supplement. So it should be – this phospholipid is of vital importance to the brain. It is a primary component of brain cell membranes. You can’t make new neurons or synapses without phosphatidylserine. Nor can you properly carry out brain cell recycling without phosphatidylserine. Our brain phospholipid levels naturally decline as we age. As such, supplementation is needed to maintain optimal cognitive performance.
DMAE – 50mg
DMAE is not a cholinergic, as is so often claimed. Instead, it seems to work by facilitating acetylcholine synthesis. We believe this is why it makes for such an unreliable focus enhancer! DMAE is nowhere near as powerful as the proper cholinergics, and nowhere near as effective when it comes to producing results. Many people get good results from 50mg per day, but a significant minority of users get side effects from the same dose. Not an great nootropic as far as we’re concerned.
Our take on the Natrogix Prime Mind formula
Natrogix got a few things right here, but they also got a few important things very wrong.
But the formula as a whole is spoiled by poor extract quality, low doses, and the inclusion of useless ingredients.
We aren’t given an extract potency for the Bacopa monnieri. This is a major red flag for us.
We use Bacopa for the bacoside content; its these compounds which produce the improvements in memory function associated with bacopa monnieri. It is standard practice to use an extract with a minimum of 20% bacosides by weight. But Natrogix haven’t told us how much of their extract is bacosides! Is it 20%? 50%? 1%? We’ve no way of knowing.
Then there’s the unproven ingredients.
Glucuronolactone has never been shown to have any positive effect on cognition. Studies have failed to show that it increases energy levels. The buzz you get from energy drinks is from the caffeine and B vitamins, not glucuronolactone. Prime Mind has no need for it.
Cordyceps mushroom looks like it might be a great all-round health supplement. Clinical trials indicate that it might bolster the immune system. But again, there’s no hard evidence that it enhances cognition in any way.
Finally, there’s the fact that Natrogix used DMAE as the main short-term focus booster in Prime Mind. Citicoline and Alpha-GPC are more expensive, but they’re more expensive for a reason. Heightened focus is one of the main functions of a nootropic as far as we’re concerned. Natrogix Prime Mind is weak on this front.
All-in-all, Natrogix Prime Mind is not a great nootropic.
Side Effects: Is Natrogix Prime Mind safe?
We think Prime Mind looks like a weak nootropic. It doesn’t pack anywhere near the ‘punch’ that the likes of Performance Lab Mind or Mind Lab Pro does.
But one consequence of being weak is that it is also highly unlikely to cause side effects!
Natrogix Prime Mind looks like a safe nootropic to us. We think 99% of you will be able to use this stack on a fairly regular basis without having to worry about side effects.
The ingredients used in Prime Mind have all been subjected to rigorous clinical trials. They are all thought to be generally safe for regular human use. We’ve never read a paper on these ingredients that raised serious health concerns.
Of course some people experience mild side effects while using herbal extracts. Bloating or nausea is rare, but it happens.
The only genuine worry is the DMAE. A significant minority of DMAE users reports some rather unpleasant side effects, including headaches, muscle cramps, jaw clenching, gurning, and hyperactivity.
If you experience any of these side effects while using Prime Mind, stop using it immediately and seek medical attention.
In Conclusion – Is Natrogix Prime Mind any good?
We’re far from impressed with this brain supplement. Natrogix have clearly made a genuine effort to produce a good nootropic with Prime Mind. It’s just that they got it completely wrong in some really important areas.
There is no one major problem with Natrogix Prime Mind.
There are several small issues.
Natrogix Prime Mind uses substandard ingredients. For example, we aren’t given an extract potency for the Bacopa monnieri, which is a major red flag for us. We have no idea how much of this Bacopa monniri extract is bacosides – it could be 50%, or it could be 0%.
The fact that we are given the extract potency for Ginkgo biloba speaks volumes – Natrogix know it is important information, yet they’ve withheld it for the Bacopa monnieri.
We aren’t given a powerful cholinergic either. Instead, Natrogix Prime Mind uses DMAE. This is an extremely unreliable, unpredictable, and ultimately weaker option than just using a proper cholinergic.
Cholinergics form the backbone of modern, professional nootropics. They produce the rapid increase in concentration, focus, and mental clarity that we associate with nootropics. The fact that Natrogix Prime Mind is missing this vital component is a serious weakness.
We do get a decent dose of Ginkgo biloba from Natrogix Prime Mind.
We also get a fair amount of caffeine – 73mg is roughly what you get from an espresso.
But that’s about it.
If you’re looking for a complete nootropic stack for total brain optimization, Natrogix Prime Mind is not it.
There are far better brain supplements out there than Natrogix Prime Mind, and for roughly similar prices too.
Brian Johnson is a former academic researcher, psychologist, and tireless proponent of bio-hacking. Brian has dedicated all of his time since leaving academia and private practice to promoting the benefits to be obtained from the application of biotechnology and bio-hacking supplements. He has years of experience with nootropics, as well as prebiotics, probiotics, and other natural nutritional supplements. He has published scholarly research on natural nootropics; you can find his papers on his Google Scholar page.