Azoth 2.0
Positives
- Anxiety and stress covered with large doses of Ashwagandha and Tyrosine
- Good serving of Alpha-GPC
Negatives
- Huperzne A needs to be cycled
- Nothing to promote neurogenesis
Summary
Azoth 2.0 is an improvement on the old Azoth formula. It is now a potent focus and learning enhancer. However, its effects will be very short-term. There’s not much long-term brain development support in Azoth 2.0. There are no antioxidants either. Hardly the most complete nootropic we’ve ever seen! You can do better for the same price.
Azoth 2.0 Review: What does it claim to do?
Azoth is a really exciting new nootropic. It was first released a little while ago, but it recently received an overhaul; the manufacturers felt like they could improve a lot on the existing formula. This, Azoth 2.0 was born! So what is this nootropic supposed to do? Who is Azoth 2.0 for exactly?
The makers of Azoth claim that this nootropic delivers four key, core benefits:
- Improved mood
- Greater energy levels
- Enhanced motivation
- Heightened focus
Very interesting! Azoth 2.0 sounds like a fantastic brain supplement; it claims to cover all of the most important short-term aspects of brain function. There’s no mention of long-term benefits or memory function on the Azoth website. But that doesn’t mean it can’t be a great nootropic.
So, does Azoth 2.0 really work like the manufacturer says? Will it cause side effects? How does it compare next to the best nootropics on the market today? Read our full Azoth 2.0 review and find out!
Azoth 2.0 Ingredients
Let’s get right into the important stuff. Here is the Azoth 2.0 formula as it appears on the bottle:
We’ll now take you through each ingredient and explain what it does – or what it’s thought to do – in more detail. If you have any questions just post them in the comments at the end.
Ashwagandha
Ashwagandha is an anxiolytic. It quickly reduces feelings of anxiety. It works by suppressing cortisol levels. Cortisol is the body’s main stress hormone; high cortisol levels cause the main physical and mental symptoms of anxiety. Ashwagandha has been used for millennia because of its ability to reduce cortisol levels in the blood. Supplementing with it is a reliable way to promote calmness and relaxation. It is also a powerful sleep aid.
Tyrosine
Like ashwagandha, Tyrosine’s main effect is anxiety-reduction. However, it is much more of a nootropic than ashwagandha. Tyrosine has proven to be particularly effective for maintaining mental clarity and focus in people subjected to intense stress – sleep deprivation, very loud noises, extreme cold, etc. Supplementing with Tyrosine is a fantastic way to support proper mental function during times of acute stress.
Phosphatidylserine
This phospholipid is of vital importance for the brain. It is found in very high concentrations in the human brain, where it is used to construct new neurons, synapses, and myelin sheaths. It is a primary structural component of brain cell membranes. It is also needed for proper inter-cellular communication, cell cycling, and more. A great nootropic for the long-term.
Sulbutiamine
This is a synthetic form of thiamine. It is used in some parts of the world as a natural cure for fatigue. However, we have serious doubts about its efficacy. Few studies have been published showing Sulbutiamine as having a meaningful effect on energy levels. We’d much rather see a good dose of caffeine instead of this unproven, synthetic substance.
Alpha-GPC
An extremely powerful cholinergic, Alpha-GPC quickly elevates acetylcholine availability in the brain. This improves practically every aspect of executive mental functioning – concentration, information processing, working memory, reaction times, and even mind-muscle connection. This is one of the most reliable, safest, and effective ways to boost focus in the short-term.
Bacopa monnieri
Bacopa monnieri is a staple of Ayurverdic medicine. Unlike many such substances, however, it has been proven to be an effective memory-enhancer. An adaptogen, Bacopa monnieri supplementation improves memory function slowly over time. The most robust clinical trials show the most pronounced effects after 8 weeks of consistent supplementation. People with mild memory impairment usually see the biggest differences.
Teacrine
In our opinion, this is a bit of an over-hyped fad. Teacrine – a branded form of the chemical theacrine – is often touted as a “caffeine alternative”. It does seem to affect adenosine signalling in a similar way to caffeine. However, every study we’ve looked at stresses how the effect is significantly weaker from theacrine compared to caffeine. So this is more of a “caffeine light” than a caffeine alternative.
Huperzine A
Huperzine A is a great supplement for rapid, short-term focus enhancement. It inhibits the enzyme acetylcholinesterase, which normally destroys acetylcholine. In doing so, it causes a steady build up of acetylcholine in the brain; the result is heightened attention, deeper concentration, and much faster processing speeds. The only issue is that it needs to be cycled or else side effects are inevitable.
Our take on the Azoth 2.0 formula
There are some major benefits to using Azoth 2.0, but on the whole we think this nootropic could be better.
Azoth 2.0 does provide a very heavy anxiolytic stack. The 250mg of Ashwagandha will significantly reduce feelings of stress and anxiety. The 250mg of Tyrosine will promote good cognitive function if you’re under serious stress. Together, these make an ideal anxiolytic stack – mental relaxation with support for concentration and information processing.
However, there are some big gaps in this formula. There’s nothing to promote long-term brain development; nothing to boost neurotrophic factors in the brain, and nothing to really promote neurogenesis.
There’s also no serious anti-oxidants in Azoth 2.0. This might be an afterthought for some of you, but protecting the brain from oxidative damage is an important job for nootropics billing themselves as complete, full-spectrum brain supplements!
There is just too much emphasis on anxiety-reduction, and not enough on focus, memory and long-term brain development.
For us, Azoth 2.0 isn’t a complete nootropic. It is, however, a great short-term focus booster.
Side Effects: Is it safe to take Azoth 2.0?
Generally speaking, Azoth 2.0 looks like a safe, side effect-free nootropic stack. We doubt many people are going to experience any adverse effect whatsoever while using this brain supplement.
The ingredients are all common nootropics; they’re widely used and very well understood. They’ve all been studied extensively, and have all been deemed perfectly safe for regular human consumption.
The only concern is the Huperzine A content. You need to cycle Huperzine A on a regular basis if you’re going to avoid side effects. Your brain needs time to let acetylcholine levels fall back to within a normal range (acetylcholinesterase is the brain’s release valve).
We recommend taking a week off after 3 weeks of using Huperzine A. You do get 50mcg of Huperzine A in Azoth, which is a relatively large dose. Maybe start with 2 weeks on, one week off.
If in doubt, message the manufacturer with your concerns.
In Conclusion – Is Azoth 2.0 a good nootropic?
Azoth 2.0 is a good nootropic, but only for people with very particular needs. It is great for a quick boost in focus, mental clarity, and a swift reduction in stress levels.
It is less effective for long-term, lasting increases in brain function.
It provides nothing for guaranteeing better brain health and functionality.
Azoth 2.0 is a nootropic for focus under pressure, not for lasting, deep cognitive enhancements.
That’s how we see it at least.
If you want something to help you get through a particularly stressful, intense week at work, then Azoth 2.0 might be just what you’re looking for.
However, if you want to make real, meaningful, lasting changes to how your brain functions, Azoth 2.0 isn’t for you!
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Brian Johnson is a former academic researcher, psychologist, and tireless proponent of bio-hacking. Brian has dedicated all of his time since leaving academia and private practice to promoting the benefits to be obtained from the application of biotechnology and bio-hacking supplements. He has years of experience with nootropics, as well as prebiotics, probiotics, and other natural nutritional supplements. He has published scholarly research on natural nootropics; you can find his papers on his Google Scholar page.
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